![]() ![]() If a rash progresses, you may develop a fever or a feeling of sickness. Alert your doctor if you detect changes in your skin. When you first start taking Zonegran (specifically during the first 2 to 4 weeks), watch closely for any signs of a rash. It may be preceded or accompanied by itchiness. The rash may take various forms, from small red spots or blotches on the surface of the skin to large blisters. If you had a history of depression before starting Zonegran, your doctor may consider other treatments such as antidepressants or referral to a counselor or psychiatrist. A slight reduction in the dosage may improve your frame of mind. If you notice mood changes with Zonegran, speak to your doctor or nurse.
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